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Same-Day Analysis

GSK Reports Highest Sales Growth in Two Years Following Relenza Boost and Currency Gains

Published: 10/29/2009

GSK has reported its strongest performance in two years, following positive currency effects and windfall sales of Relenza.

IHS Global Insight Perspective

 

Significance

GSK closes the third quarter with a strong performance boosted by the weak pound, pandemic flu vaccine sales, and emerging market growth.

Implications

As a result, GSK was able to counter the effects of negative sales growth in the United States, although this issue is likely to persist as more products face patent expiry in the near future.

Outlook

Following EU approval of its A/H1N1 flu vaccine, GSK can look forward to a stellar end-of-year performance thanks to pandemic flu vaccine sales, which are expected to fetch up to £1 billion.

U.K. pharma giant and the world's second largest pharmaceutical company GlaxoSmithKline (GSK) has reported a solid set of third-quarter results, surpassing previous expectations. Overall, total turnover amounted to £ 6.7 billion, increasing by 3% year-on-year (y/y) at a constant exchange rate (CER), and 15% y/y on a reported basis. This was largely driven by the company's pharmaceutical business, which reported revenues of £5.6 billion, a y/y increase of 2% in CER and 14% on a reported basis. The Consumer Healthcare division generated £1.2 billion and grew 8% CER y/y, well over the market growth rate of 1.5%. Operating income as calculated by IHS Global Insight was up by an impressive 31% y/y on a reported basis, with the operating margin up by 3.7 percentage points y/y, reflecting gains made following cost savings as part of GSK's restructuring programme, which remains on track to deliver cost savings of £1.7 billion by the end of 2011. On the expenses side, the cost of sales was up 11% y/y in CER to £1.7 billion, and selling, general, and administrative (SG&A) expenses were up 9% y/y to £2.1 billion. In stark contract, GSK's spending on research and development (R&D) has decreased 4% y/y to £862 billion. However, at the same time, the company has an increasing number of drugs in development, reflecting efficiency gains.

Shifting Growth Strategy

New growth areas—namely emerging markets and Japan—have become key drivers of sales, and are up 25% y/y and 19% y/y respectively at CER, reflecting the diversification of sources of growth. Meanwhile, U.S. sales were down 12% y/y, reflecting the adverse effects associated with the effects of generic competition on major products. However, European sales grew by 3% y/y. In response to the ever-increasing emphasis on new growth markets, the company has decreased its U.S. sales force by 2,200, diverting the resources to its emerging markets sales force, hiring 2,200 new sales agents in those regions in order to strengthen its foothold in those markets. Overall sales in emerging markets now account for 14% of pharmaceutical sales, a 17% y/y increase.

GSK: Selected Financial Results, Q3 2009

 

Q2 2009 (£ mil.)

% Change (reported)

% Change (CER)

Total Revenue

6,758.0

15

3

 - Pharmaceuticals

5,593.0

14

2

 - Consumer Healthcare

1,165.0

17

8

Cost of Sales

1,732.0

19

11

SG&A Expenses

2,064.0

24

9

R&D Spending

862.0

3

-4

R&D as % of Sales

12.7

2.1 pp lower

N/A

Operating Income *

2,100.0

31

N/A

Operating Margin (%) **

31.0

3.7 pp higher

N/A

Net Profit

1,480.0

25

-3

Source: GSK
* IHS Global Insight estimate: Operating income calculated as total turnover minus R&D expenses, cost of sales, and SG&A expenses.
**IHS Global Insight estimate: Operating income as a percentage of net sales
pp - percentage points
N/A - not available

On the pharmaceutical product level, growth continues to be driven by GSK's Respiratory and Antiviral portfolios, which grew 6% y/y and 15% y/y respectively, with vaccines taking a notable hit, with a reported 2% y/y decrease. Key products continue to report dwindling sales due to genericisation in the United States. The most notable ones include Lamictal (lamotrigine, down 21% to £121 million), Imigran/Imitrex (sumatriptan, down 74% to £53 million), Flonase (fluticasone propionate, down 21% to £28 million), Requip (ropinirole, down 30% to £43 million), and Wellbutrin (bupropion, down 70% to £16 million).

Strong performers include anti-viral treatment Relenza (zanamivir), which clocked sales of £182 million due to government stocking, a growth of over 100% y/y. Blockbuster drug Seretide/Advair (salmeterol/fluticasone propionate) continues to be the company's biggest seller with reported sales of £1.6 billion, a 6% y/y increase thanks to growth in Japan and emerging markets. Other notable performers include oncology drug Tyverb/Tykerb (lapatinib, up 54% to £46 million), Lovaza (omega-3-acid ethyl esters, up 27% to £111 million), and Avodart (dutasteride, up 14% to £131 million). The muted vaccine portfolio performance was attributed to troughs in vaccines tenders; however, strong performances were noted from Boostrix and Rotarix, which grew 55% y/y to £39 million and 92% y/y to £84 million, respectively.

GSK: Leading Pharmaceutical Products, Q3 2009

Brand

Q3 2009 (£ mil.)

% Change (reported)

% Change (CER)

Respiratory

1,594

18

6

Seretide/Advair (fluticasone + salmeterol)

1,152

17

5

Flixotide/Flovent (fluticasone)

169

14

-

Ventolin (salbutamol)

110

-

28

Flixonase/Flonase (fluticasone propionate)

28

-15

-21

Serevent (salmeterol)

54

-10

-18

Avamys/Veramyst (fluticasone furoate)

31

82

59

Zyrtec (cetirizine)

18

-

>100

Anti-virals

1,049

32

15

HIV

392

4

-7

Valtrex (valacyclovir)

349

15

-1

Relenza (zanamivir)

182

>100

>100

Epzicom/Kivexa (abacavir + lamivudine)

131

19

6

Combivir (zidovudine + lamivudine)

102

-7

-15

Trizivir (abacavir + lamivudine + zidovudine)

48

-2

-12

Zeffix (lamivudine)

54

28

14

Agenerase/Lexiva (fosamprenavir calcium)

43

7

-3

Epivir (lamivudine)

34

-3

-14

Ziagen (abacavir)

26

-4

-11

Central Nervous System

418

-28

-37

Lamictal (lamotrigine)

121

-11

-21

Seroxat/Paxil (paroxetine)

120

7

-12

Imigran/Imitrex (sumatriptan)

53

-72

-74

Wellbutrin, Wellbutrin XL (bupropion)

16

-70

-70

Requip (ropinirole)

43

-23

-30

Treximet (sumatriptan and naproxen sodium)

15

>100

>100

Cardiovascular and Urogenital

552

18

5

Avodart (dutasteride)

134

28

14

Lovaza (omega-3-acid ethyl esters)

111

48

27

Arixtra (fondaparinux sodium)

60

36

20

Fraxiparine (nadroprarin)

56

-5

-12

Coreg, Coreg CR (carvedilol)

39

-22

-30

Vesicare (solifenacin)

25

39

17

Levitra (vardenafil)

20

?

6

Volibris (ambrisentan)

6

?

>100

Metabolic

284

-2

-13

Avandia Products

185

-3

-14

   Avandia (rosiglitazone)

108

-8

-19

   Avandamet (rosiglitazone + metformin)

66

5

-6

Bonviva/Boniva (ibandronate sodium)

60

-7

-5

Antibacterials

376

10

3

Augmentin (amoxicillin and clavulanate)

162

13

8

Oncology and Emesis

149

16

4

Hycamtin (topotecan hydrochloride)

41

20

9

Tykerb/Tyverb (lapatinib)

46

77

54

Zofran (ondansetron)

23

-30

-33

Promacta (eltrombopag)

3

-

-

Vaccines

802

10

-2

Hepatitis

170

-2

-12

Infanrix/Pediarix

167

-0.05

-10

Rotarix

84

>100

92

Cervarix

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