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Same-Day Analysis

Ipsen's H1 Sales Up 6.3% Driven by Speciality Products

Published: 8/31/2010

French pharmaceutical company Ipsen has reported a 6.3% year-on-year increase in pharmaceutical sales for the first half of the year, boosted by double-digit growth in all specialty care therapeutic areas.

IHS Global Insight Perspective

 

Significance

Ipsen has reported sales growth of 6.3% year-on-year (y/y) within its core pharmaceutical business in the first half of 2010; once again driven by the strong performance of speciality care products, up 15.6% y/y.

Implications

Speciality care products now account for 63.6% of total group sales, up from 58.4% last year. Meanwhile, Ipsen's primary-care products have fared less well, with a sales decline of 6.9% y/y, and as a result, sales of these products as a proportion of overall sales has fallen from 38.3% in the first half of 2009 to 33.5% over the reported period.

Outlook

Ipsen has reiterated its 2010 guidance, and it expects geographic expansion in the United States and the merging markets, as well as sales growth in its speciality care portfolio to underpin growth.

French pharmaceutical company Ipsen has reported a 2.2% year-on-year (y/y) increase in its revenues for the first half of the year, to 585.7 million euro (US$743.5 million). Drug sales were up by 6.3% y/y over the period to 553.9 million euro, driven by pharmaceutical sales, which stood at 537.8 (up 6.7%), while drug-related revenues declined 6.5% y/y to 16.5 million euro. On the expenses side, the company registered a 7.2 y/y increase in selling, general, and administrative expenses, while research and development (R&D) costs increased by 8.3% y/y, with the cost of goods sold increasing by 6.3% y/y. Operating income as calculated by IHS Global Insight in turn declined by 13.9% y/y to 116.6 million euro, with net income also reported to be down by 23.7% y/y, to 75.6 million euro.

Ipsen: Selected Financial Results, 2010

 

H1 2010

Mil. Euro

% Change Y/Y

Net Revenue

585.7

2.2

Selling, General, and Administrative Costs

247.4

7.2

R&D

99.1

8.3

Cost of Goods Sold

122.6

6.3

Operating Income *

116.6

-13.9

Operating Margin

19.9%

3.7 pp lower

Net Income

75.6

-23.7

pp - percentage points
* IHS Global Insight estimate calculated as revenues minus cost of goods sold, R&D, and selling, general, and administrative costs
Source: Ipsen

Taking a closer look at Ipsen's performance in the various regions, it is clear to see that the company's presence in the North American market is slowly gaining momentum, with sales growth of 33.7%, and sales reaching 27.5 million euro, while sales growth in the rest of the world remained strong, up 11.4% y/y. Meanwhile, sales in the major Western European markets remained flat at 283.4 million euro, with the United Kingdom and France actually reporting a low single-digit decline. However, this was mitigated by minor sales growth in markets such as Spain, Italy, and Germany. The flat Western European sales have been attributed to competitive market conditions, especially in the French primary-healthcare market. In other European markets, sales were up 12.6% y/y, to 128.9 million euro.

Ipsen: H1 2010 Pharmaceutical Sales by Market (Mil. Euro)

 

H1 2010

% Change Y/Y (reported)

% Change Y/Y (at constant exchange rate)

Major Western European Markets

283.4

0

-0.2

 - France

161.4

-1.0

-1.0

 - Spain

30.5

1.6

1.6

 - Italy

40.1

3.2

3.2

 - Germany

30.5

1.6

1.6

 - United Kingdom

21.0

-1.3

-3.9

Other European Markets

128.9

12.6

11.6

North America

27.5

33.7

33.3

Rest of World (ROW)

114.2

11.1

9.0

 - Asia

60.8

10.7

9.5

 - Other ROW Markets

53.4

11.6

8.5

Group Sales

553.9

6.3

5.5

Source: Ipsen

Pharmaceutical product sales continue to receive a boost from strong sales of Ipsen's speciality care products, which were up 15.6% y/y, with double-digit growth being reported across all therapeutic areas. Metastatic prostate cancer drug Decapeptyl (triptorelin embonate) maintained its status as Ipsen's top-selling product, with revenues up 11.3% y/y to 140.8 million euro, thanks to strong sales in China and France, following the launch of the six-month sustained-release formulation of the drug in the latter. The endocrinology franchise generated sales of 120.1 million euro, a 21.7% y/y increase, with sales of Somatuline (lanreotide), NutropinAq (somatropin (rDNA origin) injection) and Increlex (mecasermin) up by 22.2%, 23.5%, and 24.4% y/y, respectively. In neurology, sales were up 15.1% y/y to 91.3 million euro, driven by Dysport (botulinum toxin type-A), which reported sales of 88.2 million, up 15.9% y/y.

Within the primary-care product portfolio, sales were down by 6.9% y/y to 185.6 million euro. The cardiovascular portfolio was the only therapeutic area to reports sales growth, up 4.6% y/y to 40 million euro, with the gastroenterology and cognitive disorder franchises reporting sales declines of 8.9% y/y and 13.7% y/y, respectively. Sales of gastroenterology product Smecta (diosmectite) were down 3.4% y/y due to lower sales in France and China. Forlax continues to suffer the effects of generic competition in France, with sales down 22.9% y/y as a result.

Ipsen: Q1 2010 Leading Pharmaceutical Sales (mil. Euro)

Therapeutic Area/Brand

Q1 2010

% Change, Y/Y (reported)

% Change, Y/Y (at constant exchange rate)

Oncology

140.8

11.3

11.2

 - Decapeptyl

140.8

11.3

11.2

Endocrinology

120.1

21.7

20.0

 - Somatuline

83.5

22.2

20.2

 - NutropinAq

23.9

23.5

22.0

 - Increlex

12.7

24.4

24.4

Neurology

91.3

15.1

12.6

 - Dysport

88.2

15.9

13.2

 - Apokyn (apomorphine)

3.1

-2.8

-2.7

Total Specialist Care

352.1

15.6

14.4

Gastroenterology

89.0

-8.9

-8.9

 - Smecta

50.4

-3.4

-3.4

 - Forlax

20.0

-22.9

-23.1

Cognitive Disorders

48.7

-13.7

-13.7

 - Tanakan (chloroquine)

48.7

-13.7

13.7

Cardiovascular

40.0

4.6

4.6

 - Nisis & Nisisco (valsartan/valsartan + hydrochlorothiazide)

29.4

5.9

5.9

 - Ginkor Fort

8.5

10.4

10.4

Other Primary-Care Products

7.9

12.3

12.3

 - Adrovance (alendronic acid + cholecalciferol)

6.3

16.6

16.6

Total Primary Care

185.6

-6.9

-6.9

Total Pharmaceutical Sales

537.8

6.7

6.0

Drug-Related Sales

16.2

-6.5

-8.1

Group Sales

553.9

6.3

5.5

Source: Ipsen

Outlook and Implications

Ipsen has once again confirmed it goals for 2010, with overall drug sales expected to grow by between 3% and 5% y/y. Sales decline of 5–7% y/y is expected for primary-care products, although this should be mitigated by strong sales growth of up to 10% y/y for specialist-care products. Taking a regional perspective, in light of the flat growth in Ipsen's core Western European market mainly stemming from austerity measure in healthcare, the company will continue to embark on geographic expansion, focusing on the U.S. market, where it has been steadily building momentum, as well as the emerging markets. The company has in the past relied on external R&D partnerships to help boost its pipeline, and the first half has been no different, with Ipsen inking deals with U.S.-based Inspiration Biopharmaceuticals for haemophilia and U.S. biotech company Dicerna Pharmaceuticals in endocrinology and oncology. As Ipsen increasingly turns to the U.S. market to boost sales, it is likely that it will embark on further U.S. partnerships as an expansion strategy.
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